5-[(trimethylsilyl)ethynyl]pyridine-2-amine
2-Amino-5-[(trimethylsilyl)ethynyl]pyridine
CAS: 457628-40-9
Molecular Formula: C10H14N2Si
5-[(trimethylsilyl)ethynyl]pyridine-2-amine - Names and Identifiers
5-[(trimethylsilyl)ethynyl]pyridine-2-amine - Physico-chemical Properties
| Molecular Formula | C10H14N2Si |
| Molar Mass | 190.32 |
| Density | 1.01 |
| Melting Point | 91-93℃ |
| Boling Point | 269℃ |
| Flash Point | 117℃ |
5-[(trimethylsilyl)ethynyl]pyridine-2-amine - Introduction
2-Amino-5-[(trimethylsilyl)ethynyl]pyridine is an organic compound with the chemical formula C10H14N2Si. It is a white solid and can exist as a powder or crystal form.
The main use of this compound is as a ligand for organometallic catalysts. It can coordinate with transition metals to form stable complexes, and is often used to catalyze various organic synthesis reactions, such as palladium-catalyzed chemical reactions of alkenes and alkynes.
The method of preparing 2-Amino-5-[(trimethylsilyl)ethynyl]pyridine is relatively simple. A common synthetic method is the reaction of 2-aminopyridine with ethynyltrimethylsilyllithium to yield the desired product. The yield of this reaction product is generally high.
Regarding safety information, 2-Amino-5-[(trimethylsilyl)ethynyl]pyridine is relatively stable under routine experimental conditions, and no serious hazards related to human health have been reported. However, as an organic compound, it still needs to be stored and handled properly to avoid contact with the skin, inhalation or ingestion. When in use, wear appropriate personal protective equipment, such as laboratory gloves and goggles, and operate in a well-ventilated area. If you accidentally come into contact with the compound, rinse immediately with water and seek medical help.
The main use of this compound is as a ligand for organometallic catalysts. It can coordinate with transition metals to form stable complexes, and is often used to catalyze various organic synthesis reactions, such as palladium-catalyzed chemical reactions of alkenes and alkynes.
The method of preparing 2-Amino-5-[(trimethylsilyl)ethynyl]pyridine is relatively simple. A common synthetic method is the reaction of 2-aminopyridine with ethynyltrimethylsilyllithium to yield the desired product. The yield of this reaction product is generally high.
Regarding safety information, 2-Amino-5-[(trimethylsilyl)ethynyl]pyridine is relatively stable under routine experimental conditions, and no serious hazards related to human health have been reported. However, as an organic compound, it still needs to be stored and handled properly to avoid contact with the skin, inhalation or ingestion. When in use, wear appropriate personal protective equipment, such as laboratory gloves and goggles, and operate in a well-ventilated area. If you accidentally come into contact with the compound, rinse immediately with water and seek medical help.
Last Update：2024-04-10 22:29:15
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